ULK4 polyclonal antibody

• Background:

  The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Serine/threonine-protein kinase ULK4; Unc-51-like kinase 4; ULK4

• Swiss Prot:

  Q96C45

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length Human ULK4.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC IF

• Dilution:

  WB: 1:500~1:2000 IHC/IF: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 160 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  ULK4 polyclonal antibody detects endogenous levels of ULK4 protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using ULK4 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4