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LPHN2 polyclonal antibody

CAT: 0384-BS60779-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60779-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Latrophilin-2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Latrophilin homolog 1; Lectomedin-1; LPHN2; KIAA0786; LEC1; LPHH1
Swiss Prot
O95490
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human LPHN2
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 220 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LPHN2 polyclonal antibody detects endogenous levels of LPHN2 protein.
Applications Notes
Western blot (WB) analysis of LPHN2 pAb at 1:500 dilution Lane1:U-87MG whole cell lysate (40ug) Lane2:H1792 whole cell lysate (40ug) Lane3:HepG2 whole cell lysate (40ug)
Host or Source
Rabbit

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