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MYBPC1 polyclonal antibody

CAT: 0384-BS62406-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62406-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MYBPC1, also known as MYBPCS (myosin-binding protein C, slow-type) or MyBP-C, is a 1,141 amino acid protein that contains 3 fibronectin type-III domains and 7 Ig-like C2-type domains. Existing as a member of the immunoglobulin superfamily, MYBPC1 functions as a thick filament-associated protein that localizes to striated muscle bands in vertebrae and is thought to modify the activity of select ATPases. Additionally, MYBPC1 may play a role in the modulation of muscle contraction and in the overall structural integrity of the cell. The gene encoding MYBPC1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Myosin-binding protein C, slow-type; Slow MyBP-C; C-protein, skeletal muscle slow isoform; MYBPC1; MYBPCS
Swiss Prot
Q00872
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to Human MYBPC1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:500~1:1000
Purity
The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 128 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MYBPC1 polyclonal antibody detects endogenous levels of MYBPC1 protein.
Applications Notes
Western blot (WB) analysis of MYBPC1 polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:PC12 whole cell lysate
Host or Source
Rabbit

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