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GBA3 polyclonal antibody

CAT: 0384-BS62347-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62347-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytosolic beta-glucosidase, neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides. Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear. Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear. It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics. Could also play a role in the catabolism of cytosolic sialyl free N-glycans.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; Cytosolic glycosylceramidase; Cytosolic GCase; Glucosidase beta acid 3; Glucosylceramidase beta 3; Klotho-related protein; KLrP; GBA3; CBG; CBGL1
Swiss Prot
Q9H227
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human GBA3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 54 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GBA3 polyclonal antibody detects endogenous levels of GBA3 protein.
Applications Notes
Western blot (WB) analysis of GBA3 polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:HepG2 whole cell lysate LaneC:CT26 whole cell lysate LaneD:The Liver tissue lysate of Rat
Host or Source
Rabbit

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