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CPD polyclonal antibody

CAT: 0384-BS60812-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60812-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. CPD (carboxypeptidase D), also known as GP180 or metallocarboxypeptidase D, is a 1,380 amino acid single-pass type I membrane protein that belongs to the peptidase M14 family. CPD binds two zinc ions per subunit and contains three carboxypeptidase-like domains. CPD causes the release of C-terminal arganine and lysine from polypeptides. Highest expression of CPD is found in pancreas, hepatoma cells and placenta, with lower levels in heart, skeletal muscle and colon carcinoma. Mammalian CPD is a homolog of the duck hepatitis B virus-binding protein gp180.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Carboxypeptidase D; Metallocarboxypeptidase D; gp180; CPD
Swiss Prot
O75976
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human CPD.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 200 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CABIN1 polyclonal antibody detects endogenous levels of CABIN1 protein.
Applications Notes
Western blot (WB) analysis of CPD pAb at 1:500 dilution Lane1:U-87MG whole cell lysate (40ug) Lane2:SGC7901 whole cell lysate (40ug)
Host or Source
Rabbit

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