ERN2 Polyclonal Antibody

• Background :

  ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins.

• CAS Number :

  9007-83-4

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN.

• Swiss Prot :

  O75460

• Reactivity :

  Human, Mouse, Rat, Dog, Pig, Cow, Sheep

• Immunogen :

  KLH conjugated synthetic peptide derived from human ERN2:465-550/926

• Conjugation :

  Unconjugated

• Applications :

  FCM

• Dilution :

  Flow-Cyt=2ug/Test

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  98kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  ERN2 Polyclonal Antibody detects endogenous levels of ERN2 protein.

• Host or Source :

  Rabbit