Upstream Binding Protein 1 Polyclonal Antibody

• Background:

  Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity) . Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

• Structure Composition:

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative:

  LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.

• Swiss Prot:

  Q9NZI7

• Reactivity:

  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse

• Immunogen:

  KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB=1:500-2000

• Purity:

  Affinity purified by Protein A

• Modification:

  Unmodification

• Molecular Weight:

  56 kD

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Upstream Binding Protein 1 Polyclonal Antibody detects endogenous levels of Upstream Binding Protein 1 protein.

• Applications Notes:

  Primary: Anti- Upstream Binding Protein 1 at 1/1000 dilution

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4