Products for Research Use Only
RegisterLogin

FREAC3 Polyclonal Antibody

CAT: 0384-BS65958-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS65958-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Involvement in disease; Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3) ; also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
ARA; FKH L7; FKHL 7; FKHL7; Forkhead (Drosophila) like 7; Forkhead; forkhead box C1; Forkhead box protein C1; Forkhead drosophila homolog like 7; Forkhead like 7; Forkhead related activator 3; Forkhead related protein FKHL7; Forkhead related transcription factor 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FOX C1; FOXC 1; FOXC1; FOXC1_HUMAN; FREAC 3; FREAC-3; FREAC3; homolog-like 7; IGDA; IHG 1; IHG1; IRID 1; IRID1; Iridogoniodysgenesis type 1; Myeloid factor delta.
Swiss Prot
Q12948
Reactivity
Human, Mouse, Rat, Chicken, Dog, Cow, Horse
Immunogen
KLH conjugated synthetic peptide derived from human FOXC1/FREAC3:101-200/553
Conjugation
Unconjugated
Applications
IHC-P, FCM
Dilution
IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
57kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FREAC3 Polyclonal Antibody detects endogenous levels of FREAC3 protein.
Applications Notes
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH 6.0), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Incubation: Anti-FOXC1/FREAC3 Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C
Host or Source
Rabbit

Related Products

CatalogName
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS5662-01CHST1 polyclonal antibody
BS71123-01COPS7A polyclonal antibody
BS65479-01GDN Polyclonal Antibody
BS8691-01TUSC2 polyclonal antibody
BS72779-01FBLIM1 polyclonal antibody
BZ16836APE1 polyclonal antibody
BS90894MUC2 polyclonal antibody
BS71148-01LLGL2 polyclonal antibody

Alternative Products

CatalogName
GTR18048666-01FREAC3 Polyclonal Antibody
GTR17728031-01FREAC3 Rabbit Polyclonal Antibody
TMAB-06163-01Anti-FREAC3 Polyclonal Antibody
GTR17757462FREAC3 Rabbit Polyclonal Antibody (PE)
GTR18247068FREAC3 Rabbit Polyclonal Antibody (BF594)
GTR18247057FREAC3 Rabbit Polyclonal Antibody (BF647)
GTR18462685FREAC3 Rabbit Polyclonal Antibody (BF700)
GTR18314100FREAC3 Rabbit Polyclonal Antibody (PerCP)
GTR18314098FREAC3 Rabbit Polyclonal Antibody (BF680)
GTR17821123FREAC3 Rabbit Polyclonal Antibody (APC)

Popular Products