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IFT46 Polyclonal Antibody

CAT: 0384-BS65787-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65787-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFT46 is a 304 amino acid protein that belongs to the IFT46 family. IFT46 localizes to the cilium basal body but can also be found along the length of the cilium and is a part of a complex involved in intraflagellar transport (IFT) . In addition, IFT46 is involved in the bi-directional movement of particles that is required for the assembly, maintenance, and functionality of primary cilia. Furthermore, IFT46 may be involved in skeletogenesis and chondrocyte maturation. Two isoforms exist due to alternate splicing events and the gene encoding IFT46 maps to human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
C11orf2; C11orf60; IFT46; IFT46_HUMAN; Intraflagellar transport protein 46 homolog.
Swiss Prot
Q9NQC8
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human IFT46:101-200/304
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
34 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IFT46 Polyclonal Antibody detects endogenous levels of IFT46 protein.
Applications Notes
Primary: Anti-IFT46 at 1/1000 dilution
Host or Source
Rabbit

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