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CCDC7 Polyclonal Antibody

CAT: 0384-BS65410-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65410-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. Some proteins that contain coil-coiled domains include c-jun, c-fos and tropomyosin. Coiled-coil domains consist of two or more ?helices packed together via interlacing side chains. CCDC7 (Coiled-coil domain-containing protein 7) is a 486 amino acid protein that contains a coiled-coil domain and is encoded by a gene that maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. There are two isoforms of CCDC7 that are produced as a result of alternative splicing events.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
BioT2 A; BioT2 B; BioT2 C; CCDC 7; Coiled coil domain containing 7; Coiled coil domain containing protein 7; CCDC7_HUMAN.
Swiss Prot
Q96M83
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse
Immunogen
KLH conjugated synthetic peptide derived from human CCDC7:155-250/486
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
56 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CCDC7 Polyclonal Antibody detects endogenous levels of CCDC7 protein.
Applications Notes
Primary: Anti- CCDC7 (bs-7991R) at 1/1000 dilution
Host or Source
Rabbit

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