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NR6A1 polyclonal antibody

CAT: 0384-GCP62-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-GCP62-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GCNF (Germ Cell Nuclear Factor), also known as NR6A1 (Nuclear Receptor Subfamily 6 Group A member), is an orphan member of the nuclear receptor gene superfamily. It has been shown to be expressed in the nervous system during development and during specific stages in maturing germ cells of the ovary and testis in the adult, and has probable roles in gametogenesis, neurogenesis, and normal embryonic development during gastrulation. Inactivation of GCNF in mouse results in abnormal posterior development, impaired midbrain development, insufficient closure of the neural tube, and eventual embryonic death. GCNF has been shown to be a repressor of OCT-4 and of the protamine genes and plays a critical role in the control of gene expression during embryogenesis and spermatogenesis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Nuclear receptor subfamily 6 group A member 1; Germ cell nuclear factor; GCNF; hGCNF; Retinoid receptor-related testis-specific receptor; RTR; hRTR; NR6A1; GCNF
Swiss Prot
Q15406
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to Human NR6A1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000~1:5000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NR6A1 polyclonal antibody detects endogenous levels of NR6A1 protein.
Applications Notes
Western blot (WB) analysis of NR6A1 polyclonal antibody at 1:2000 dilution Lane1:Hela whole cell lysate (40ug) Lane2:HepG2 whole cell lysate (40ug) Lane3:K562 whole cell lysate (40ug)
Host or Source
Rabbit

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