C4BP beta polyclonal antibody

• Background:

  Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

• Structure Composition:

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative:

  C4b-binding protein beta chain

• Swiss Prot:

  P20851

• Reactivity:

  Human

• Immunogen:

  Recombinant full length protein of human C4BP beta

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF/ICC

• Dilution:

  WB (1/500 - 1/2000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/100)

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 28 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of C4BP beta protein.

• Applications Notes:

  Western blot analysis of C4BP beta expression in HepG2 (A), mouse testis (B), rat testis (C) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4