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IKK beta polyclonal antibody

CAT: 0384-BZ16751-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16751-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins (1-3) . Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IκB (3-7) . The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
IKBKB; IKKB; Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
Swiss Prot
O14920
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human IKK beta
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 87 kDa; Observed MW: 87 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of IKK beta in HeLa lysates using IKK beta antibody.
Host or Source
Rabbit

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