BATF3 polyclonal antibody

• Background :

  AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity) . Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.

• CAS Number :

  9007-83-4

• Structure Composition :

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative :

  SNFT; Basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT

• Swiss Prot :

  Q9NR55

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BATF3. The exact sequence is proprietary.

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB (1/500 - 1/1000)

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 225% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 14 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Recognizes endogenous levels of BATF3 protein.

• Applications Notes :

  Western blot analysis of BATF3 expression in mouse lung (A), mouse spleen (B) whole cell lysates.

• Host or Source :

  Rabbit