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BEND4 polyclonal antibody

CAT: 0384-BS67239-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67239-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
CCDC4; BEN domain-containing protein 4; Coiled-coil domain-containing protein 4
Swiss Prot
Q6ZU67
Reactivity
Human, Mouse
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BEND4. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 200% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 58, 46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of BEND4 protein.
Applications Notes
Western blot analysis of BEND4 expression in SGC7901 (A), EC9706 (B), mouse liver (C) whole cell lysates.
Host or Source
Rabbit

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