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IRF3 (phospho-S396) polyclonal antibody

CAT: 0384-BS67168-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67168-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Key transcriptional regulator of type I interferon (IFN) -dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses (PubMed:22394562, PubMed:25636800, PubMed:27302953) .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Interferon regulatory factor 3; IRF-3
Swiss Prot
Q14653
Reactivity
Human, Rat, Mouse
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human IRF3 (pS396) . The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Toll-like Receptor signaling
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 129% (by SDS-PAGE) .
Modification
Phosphorylation
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of IRF3 (pS396) protein.
Applications Notes
Western blot analysis of IRF3 (pS396) expression in HepG2 (A), mouse muscle (B), rat muscle (C) whole cell lysates.
Host or Source
Rabbit

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