IRF3 polyclonal antibody

• Background:

  IRFs comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  IRF3; Interferon regulatory factor 3; IRF-3

• Swiss Prot:

  Q14653

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human IRF3

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, FC

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 47 kDa; Observed MW: 57 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of IRF3 in HeLa lysates; 3T3 lysates using IRF3 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4