Products for Research Use Only
RegisterLogin

IRF3 (Phospho-S386) polyclonal antibody

CAT: 0384-BS94024-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS94024-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
IRF-3, IRF3, IIAE7, Interferon regulatory factor 3, IRF 3, IRF-3, IRF3, IRF3, MGC94729
Swiss Prot
Q14653
Reactivity
Human
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser386 of human IRF3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylated
Molecular Weight
~ 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IRF3 (Phospho-S386) polyclonal antibody detects endogenous levels of IRF3 protein only when phosphorylated at S386.
Applications Notes
Western blot analysis of IRF3 (Phospho-S386) expression in Hela-LPS (A), HepG2 (B) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS4609-01IRF3 (Phospho-S385) polyclonal antibody
BS4609-IRF3 (Phospho-S385) polyclonal antibody
BS2508-01Aiolos (S386) polyclonal antibody
BS67168-01IRF3 (phospho-S396) polyclonal antibody
BS67545-01IRF3 (Phospho-S396) polyclonal antibody
BS67599IRF3 polyclonal antibody
BS67199IRF3 polyclonal antibody
BZ16696-01IRF3 polyclonal antibody
BS6921IRF3 polyclonal antibody
BS90738IRF3 polyclonal antibody

Alternative Products

CatalogName
GTR18047577-01IRF3 (Phospho-S386) polyclonal antibody
MBS7121441-01Phospho-IRF3 (S386) Antibody
E51A09665IRF3 (Phospho-S386) Antibody
GTR18701963-01IRF3 (Phospho-S386) Rabbit Polyclonal Antibody
bsm-54508RPhospho-IRF3 (S386) Monoclonal Antibody
RC-15236-01Recombinant IRF3 (phospho S386) Antibody
MBS8327198-01Anti-IRF3 (Phospho-S386) Antibody
MBS9456127-01IRF3 (Phospho-S386) Conjugated Antibody
STJ11100998Anti-Phospho-IRF3-S386 antibody
RAC07614-01Phospho-Irf3 (S386) Recombinant Antibody

Popular Products