FASTKD2 polyclonal antibody

• Background:

  Plays an important role in assembly of the mitochondrial large ribosomal subunit (PubMed:25683715) .As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664, PubMed:25683715, PubMed:26370583) .May play a role in mitochondrial apoptosis.

• Structure Composition:

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative:

  KIAA0971; FAST kinase domain-containing protein 2

• Swiss Prot:

  Q9NYY8

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FASTKD2. The exact sequence is proprietary.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB (1/500 - 1/1000)

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 95 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of FASTKD2 protein.

• Applications Notes:

  Western blot analysis of FASTKD2 expression in H446 (A), A549 (B), mouse liver (C), mouse lung (D), rat liver (E), rat lung (F) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4