SCN4B polyclonal antibody

• Background:

  Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Sodium channel subunit beta-4; SCN4B

• Swiss Prot:

  Q8IWT1

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide, corresponding to Human SCN4B.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC

• Dilution:

  WB: 1:500~1:1000 IHC: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 25 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  SCN4B polyclonal antibody detects endogenous levels of SCN4B protein.

• Applications Notes:

  Western blot (WB) analysis of SCN4B polyclonal antibody at 1:500 dilution LaneA:The Kidney tissue lysate of Mouse (40ug) LaneB:The Lung tissue lysate of Mouse (40ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4