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IL-33 polyclonal antibody

CAT: 0384-BS67773-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67773-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-33 (Interleukin-33, NF-HEV) is a nuclear cytokine that is part of the IL-1 family (1,2) . Originally discovered as the ‘nuclear factor from high endothelial venules, ’ it is widely expressed by endothelial cells as well as epithelial barrier tissues. IL-33 is involved in regulating type 2-associated innate immune responses. It is the ligand for ST2 which, along with IL-1RAcP, forms the IL-33R signaling complex. IL-33 functions as an alarmin upon cellular damage or stress, and is associated with allergic inflammation and asthma.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
C9orf26; IL1F11; NFHEV; Interleukin-33; IL-33; Interleukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules; NF-HEV
Swiss Prot
O95760
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein corresponding to human IL-33. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/100)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 31 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of IL-33 protein.
Applications Notes
Western blot analysis of IL-33 expression in A549 (A), mouse lung (B), rat lung (C) whole cell lysates.
Host or Source
Rabbit

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