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OCT1 (Phospho-S385) polyclonal antibody

CAT: 0384-BS67588-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67588-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain . Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc , OBF-1 (a B-cell transcriptional coactivator protein), TFIIB , and TBP (TATA-box-binding protein) . Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
POU2F1; OCT1; OTF1; POU domain class 2 transcription factor 1; NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1; POU2F2; OCT2; OTF2; POU domain class 2 transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2
Swiss Prot
P14859; P09086
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human OCT1 with a phosphorylation site at S385. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Phosphorylation
Molecular Weight
~ 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of OCT1 with a phosphorylation site at S385 protein.
Applications Notes
Western blot analysis of OCT1 (pS385) expression in mouse lung (A), rat lung (B) whole cell lysates.
Host or Source
Rabbit

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