Products for Research Use Only
RegisterLogin

JNK1/2/3 polyclonal antibody

CAT: 0384-BS80221-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS80221-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
JNK belongs to MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1, JNK2, and JNK3
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss Prot
P45983/P45984/P53779
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human JNK1/2/3 (NP_620637.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC, IP
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200|IP,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
46kDa/54kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

Related Products

CatalogName
BS65605-01JNK1+JNK2+JNK3 Polyclonal Antibody
BS3630-01JNK1/2/3 (T178) polyclonal antibody
BS1544-01JNK1/2/3 (P184) polyclonal antibody
BS3631JNK1/2/3 (Y185) polyclonal antibody
BZ16734-01JNK1/3 polyclonal antibody
BS90752JNK1/3 polyclonal antibody
BS4763-01JNK1/2/3 (phospho-T183) polyclonal antibody
BS4764-01JNK1/2/3 (Phospho-Y185) polyclonal antibody
AP0370JNK1/2/3 (T183/Y185) polyclonal antibody
AP0252-01JNK1/2/3 (Phospho-T183/Y185) polyclonal antibody

Alternative Products

CatalogName
JOT-AP04705-01JNK1/2/3 Polyclonal Antibody

Popular Products