IKKε polyclonal antibody

• Background:

  IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  IKBKE; IKK-E; IKK-i; IKKE; IKKI

• Swiss Prot:

  Q14164

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human IKKε (NP_001180251.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IP

• Dilution:

  WB,1:500 - 1:2000|IHC,1:50 - 1:200|IP,1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  110kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Unmodification

• Applications Notes:

  Immunoprecipitation analysis of 200ug extracts of K-562 cells, using 3 ug IKKε antibody . Western blot was performed from the immunoprecipitate using IKKε antibody at a dilution of 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4