IKKε polyclonal antibody

• Background :

  IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  IKBKE; IKK-E; IKK-i; IKKE; IKKI

• Swiss Prot :

  Q14164

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human IKKε (NP_001180251.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, IP

• Dilution :

  WB,1:500 - 1:2000|IHC,1:50 - 1:200|IP,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  110kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Applications Notes :

  Immunoprecipitation analysis of 200ug extracts of K-562 cells, using 3 ug IKKε antibody . Western blot was performed from the immunoprecipitate using IKKε antibody at a dilution of 1:1000.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4