CHN2 polyclonal antibody

• Background:

  This gene encodes a guanosine triphosphate (GTP) -metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG) -type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG) . Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CHN2; ARHGAP3; BCH; CHN2-3; RHOGAP3

• Swiss Prot:

  P52757

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human CHN2 (NP_004058.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB,1:200 - 1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  54kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Unmodification

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4