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APBA1 polyclonal antibody

CAT: 0384-BS77828-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS77828-01Size:50 µL
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Background
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA; APBA1
Swiss Prot
Q02410
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human APBA1 (NP_001154.2) .
Conjugation
Unconjugated
Applications
IHC, IF/ICC
Dilution
IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
Refer to figures
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Applications Notes
Immunohistochemistry of paraffin-embedded mouse brain using APBA1 Rabbit pAb at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Host or Source
Rabbit