PGRMC2 polyclonal antibody

• Background :

  Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity. May serve as a universal non-classical progesterone receptor in the uterus (Probable. Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity.

• CAS Number :

  9007-83-4

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  PGRMC2; DG6; PMBP

• Swiss Prot :

  O15173

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human PGRMC2 (NP_006311.3) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC

• Dilution :

  WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  23kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Host or Source :

  Rabbit