PHC3 polyclonal antibody

• Background:

  Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  PHC3; EDR3; HPH3

• Swiss Prot:

  Q8NDX5

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human PHC3 (NP_079223.3) .

• Conjugation:

  Unconjugated

• Applications:

  IF/ICC

• Dilution:

  IF/ICC,1:50 - 1:100

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Unmodification

• Applications Notes:

  Immunofluorescence analysis of U2OS cells using PHC3 antibody . Blue: DAPI for nuclear staining.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4