POLE2 polyclonal antibody

• Background :

  DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B) . Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  POLE2; DPE2

• Swiss Prot :

  P56282

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human POLE2 (NP_002683.2) .

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB,1:500 - 1:2000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  59kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4