Products for Research Use Only
RegisterLogin

PGLYRP1 polyclonal antibody

CAT: 0384-BS74510-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS74510-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems. Acts as a pattern receptor that binds to murein peptidoglycans (PGN of Gram-positive bacteria and thus provides bactericidal activity. Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane. In addition, acts in complex with the Ca (2+-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement. Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system. Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity. Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PGLYRP1; PGLYRP; PGRP; PGRP-S; PGRPS; TAG7; TNFSF3L
Swiss Prot
O75594
Reactivity
Human
Immunogen
Recombinant fusion protein of human PGLYRP1 (NP_005082.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
35kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

Related Products

CatalogName
BS77503-01PGLYRP2 polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS65563-01Mras polyclonal antibody
BS7930-01TRPM2 polyclonal antibody
BS8744-01TPH2 polyclonal antibody
BS62356-01CSP polyclonal antibody
BS90079ApoER2 polyclonal antibody
BS8248-01NGB polyclonal antibody
BS91398UBC9 polyclonal antibody

Alternative Products

CatalogName
JOT-AP07104-01PGLYRP1 Polyclonal Antibody
E53P08479PGLYRP1 Rabbit Polyclonal Antibody

Popular Products