C-Kit polyclonal antibody

• Background:

  KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117

• Swiss Prot:

  P10721

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human c-Kit. AA range:688-737

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-F, IHC-P, ICC/IF, ELISA

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 110 kDa; Observed MW: 120 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded Human Mammary cancer using c-Kit antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4