AVPR1B polyclonal antibody

• Background:

  The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor

• Swiss Prot:

  P47901

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320

• Conjugation:

  Unconjugated

• Applications:

  IHC-P, ELISA

• Dilution:

  IHC: 1/50-1/100 ELISA: 1/10000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded Human brain using AVPR1B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4