TLE1/2/3/4 polyclonal antibody

• Background:

  Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  TLE1; Transducin-like enhancer protein 1; E (Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2; TLE3; KIAA1547; Transducin-like enhancer protein 3; Enhance

• Swiss Prot:

  Q04724/Q04725/Q04726/Q04727

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TLE1/2/3/4.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1/500-1/2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 82 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  TLE1/2/3/4 polyclonal antibody detects endogenous levels of TLE1/2/3/4 protein.

• Applications Notes:

  Western blot analysis of TLE1/2/3/4 expression in A549 (A), K562 (B), Hela (C), NIH3T3 (D), mouse liver (E) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4