Products for Research Use Only

TLE1 monoclonal antibody

CAT: 0384-MB67073-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-MB67073-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors, such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Transducin-like enhancer protein 1; E (Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1
Swiss Prot
Q04724
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TLE1. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Wntβ catenin signaling
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of TLE1 protein.
Applications Notes
Western blot analysis of TLE1 expression in A549 (A) whole cell lysates.
Host or Source
Mouse