CD167a polyclonal antibody

CAT: 0384-NCP0289P-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-NCP0289P-01Size:50 µL
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Background
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; DDR1; CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE
Swiss Prot
Q08345
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human CD167a.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:1000~1:2000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD167a polyclonal antibody detects endogenous levels of CD167a protein.
Applications Notes
Western blot (WB) analysis of CD167a polyclonal antibody at 1:1000 dilution Lane1:BV2 whole cell lysate (30ug) Lane2:PC12 whole cell lysate (30ug) Lane3:MCF-7 whole cell lysate (30ug) Lane4:A375 whole cell lysate (30ug) Lane5:HEK293T whole cell lysate (30ug)
Host or Source
Rabbit

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