CD159a polyclonal antibody

CAT: 0384-NCP0284P-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-NCP0284P-01Size:50 µL
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Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
KLRC1; NKG2A; CD159A; NKG2-A/NKG2-B type II integral membrane protein
Swiss Prot
P26715
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human CD159a.
Conjugation
Unconjugated
Applications
IF
Dilution
IF: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD159a polyclonal antibody detects endogenous levels of CD159a protein.
Applications Notes
Immunofluorescence analysis of MG63 cells using CD159a pAb at dilution of 1:200 (40x lens) .
Host or Source
Rabbit

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