CD159a polyclonal antibody

• Background :

  Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative :

  KLRC1; NKG2A; CD159A; NKG2-A/NKG2-B type II integral membrane protein

• Swiss Prot :

  P26715

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Recombinant protein of human CD159a.

• Conjugation :

  Unconjugated

• Applications :

  IF

• Dilution :

  IF: 1:100~1:500

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodified

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CD159a polyclonal antibody detects endogenous levels of CD159a protein.

• Applications Notes :

  Immunofluorescence analysis of MG63 cells using CD159a pAb at dilution of 1:200 (40x lens) .

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4