RegisterLogin

Klotho Polyclonal Antibody

CAT: 0384-BS65616-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65616-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity) . Essential factor for the specific interaction between FGF23 and FGFR1. The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
KL antibody KLOT_HUMAN; Klotho peptide
Swiss Prot
Q9UEF7
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KL (NP_004786.2) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 116 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Klotho Polyclonal Antibody detects endogenous levels of Klotho protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using KL antibody at 1:3000 dilution.
Host or Source
Rabbit

Related Products

CatalogName
BS40698-01Klotho Rabbit monoclonal antibody
BS48140Klotho Recombinant Rabbit mAb
CEK2026Human Klotho ELISA Kit
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS60703-01LILRB polyclonal antibody
BS66191-01FEZ1 polyclonal antibody
BS66193-01LIAS polyclonal antibody
BS66202-01SLC31A1 polyclonal antibody
BS66213-01C1qa polyclonal antibody
BS66227-01UTP20 polyclonal antibody

Alternative Products

CatalogName
APR08108GPolyclonal KLOTHO Antibody
bs-2925RKlotho Polyclonal Antibody
TMAB-01030-01Anti-Klotho Polyclonal Antibody
GTR04026890-01Polyclonal Antibody to Klotho (KL)
CAU21883-01Klotho (KL) Polyclonal Antibody
NBP1-76511Rabbit Polyclonal Klotho Antibody
NB100-2432Goat Polyclonal Klotho Antibody
AF7338KL/Klotho Rabbit Polyclonal Antibody
TA346110Klotho (KL) Rabbit Polyclonal Antibody
MBS2006182-01Polyclonal Antibody to Klotho Beta (KLb)

Popular Products