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GLP2R polyclonal antibody

CAT: 0384-BS8286-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8286-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R) .
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
GLP 2 R; GLP 2 receptor; GLP 2R; GLP-2 receptor; GLP-2-R; GLP-2R; GLP2 R; GLP2 Receptor; GLP2R; GLP2R_HUMAN; Glucagon Like Peptide 2 Receptor; Glucagon-like peptide 2 receptor
Swiss Prot
O95838
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R (NP_004237.1) .
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB: 1:100-1:500 IHC-P: 1:50-1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 67 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GLP2R polyclonal antibody detects endogenous levels of GLP2R protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using GLP2R antibody at 1:500 dilution.
Host or Source
Rabbit

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