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HMOX1 polyclonal antibody

CAT: 0384-BS3978-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3978-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme that results in the release of carbon monoxide, iron, and biliverdin. The products of this enzymatic reaction play important biological roles in antioxidant, anti-inflammatory, and cytoprotective functions. HO comprises two isozymes, including the constitutively expressed HO-2 isozyme and the inducible HO-1 isozyme. Inducible HO-1 is expressed as an adaptive response to several stimuli, including heme, metals, and hormones. The induction of HO-1 has been implicated in numerous disease states, such as transplant rejection, hypertension, atherosclerosis, Alzheimer's disease, endotoxic shock, diabetes, inflammation, and neurological disorders.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Heme oxygenase 1; HO-1; Heme oxygenase 1 soluble form; HMOX1; HO; HO1
Swiss Prot
P09601
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human HMOX1.
Conjugation
Unconjugated
Applications
WB IP
Dilution
WB: 1:1000~1:2000 IP: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 32 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HMOX1 polyclonal antibody detects endogenous levels of HMOX1 protein.
Applications Notes
Western blot (WB) analysis of HMOX1 polyclonal antibody at 1:1000 dilution Lane1:HepG2 whole cell lysate (30ug) Lane2:A549 whole cell lysate (30ug) Lane3:A2780 whole cell lysate (30ug) Lane4:The Spleen tissue lysate of Mouse (30ug) Lane5:PMVEC whole cell lysate (30ug)
Host or Source
Rabbit

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