CTDSP1 polyclonal antibody

• Background:

  Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Nuclear LIM interactor-interacting factor 3; NLI-IF; NLI-interacting factor 3; Small C-terminal domain phosphatase 1; SCP1; Small CTD phosphatase 1; CTDSP1; NIF3, NLIIF, SCP1

• Swiss Prot:

  Q9GZU7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding Human CTDSP1.

• Conjugation:

  Unconjugated

• Applications:

  WB IP

• Dilution:

  WB: 1:500~1:1000 IP: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 29 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CTDSP1 polyclonal antibody detects endogenous levels of CTDSP1protein.

• Applications Notes:

  Western blot (WB) analysis of CTDSP1 polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate (40ug) Lane2:PMVEC whole cell lysate (40ug) Lane3:H1792 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4