Piperonyl butoxide (Standard)

Piperonyl butoxide (Standard)

• CAS Number: 51-03-6
• UNSPSC Description: Piperonyl butoxide (Standard) is the analytical standard of Piperonyl butoxide. This product is intended for research and analytical applications. Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice[1][2][3].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/piperonyl-butoxide-standard.html
• Solubility: 10 mM in DMSO
• Smiles: CCCC1=C(COCCOCCOCCCC)C=C2OCOC2=C1
• Molecular Weight: 338.44
• References & Citations: [1]Muguruma M, et al. Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Arch Toxicol. 2008 Oct;82(10):749-53.|[2]Tanaka T, et al. Effects of piperonyl butoxide on exploratory behaviour in female mice. Toxicol Ind Health. 2019 Apr;35(4):314-323.|[3]Takahashi O, et al. Chronic toxicity studies of piperonyl butoxide in CD-1 mice: induction of hepatocellular carcinoma. Toxicology. 1997 Dec 26;124(2):95-103.
• Shipping Conditions: Room temperature
• Clinical Information: Launched