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Piperonyl butoxide

CAT: 0804-HY-B1198-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1198-01Size:100 mg
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Description
Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice[1][2][3].
CAS Number
51-03-6
Product Name Alternative
ENT-14250
UNSPSC
12352005
Hazard Statement
H319, H335, H400, H410
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Piperonyl-butoxide.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
CCCC1=C(COCCOCCOCCCC)C=C2OCOC2=C1
Molecular Formula
C19H30O5
Molecular Weight
338.44
Precautions
H319, H335, H400, H410
References & Citations
[1]Muguruma M, et al. Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Arch Toxicol. 2008 Oct;82 (10) :749-53.|[2]Tanaka T, et al. Effects of piperonyl butoxide on exploratory behaviour in female mice. Toxicol Ind Health. 2019 Apr;35 (4) :314-323.|[3]Takahashi O, et al. Chronic toxicity studies of piperonyl butoxide in CD-1 mice: induction of hepatocellular carcinoma. Toxicology. 1997 Dec 26;124 (2) :95-103.|[4]Jenkins AE, et al. Pharmacokinetic analysis of acute and dietary exposure to piperonyl butoxide in the mouse. Toxicol Rep. 2023 Sep 23;11:310-317.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched