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R- (+) -Cotinine

CAT: 0804-HY-B1178A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1178A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R- (+) -Cotinine ((+) -Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R- (+) -Cotinine can enhance the Ach-evoked current in human α7 nAChRs[1].
CAS Number
32162-64-4
Product Name Alternative
(+) -Cotinine; (R) -Cotinine; (R) -NIH-10498
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-plus-cotinine.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)[C@@H](C2=CC=CN=C2)CC1
Molecular Formula
C10H12N2O
Molecular Weight
176.22
References & Citations
[1]Jr AVT, et, al. R- (+) and S- (-) isomers of cotinine augment cholinergic responses in vitro and in vivo. J Pharmacol Exp Ther. 2015 Feb;352 (2) :405-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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