Cotinine N-β-D-Glucuronide

• Description:

  Cotinine N-β-D-Glucuronide is a glucuronide conjugate of the tobacco metabolite Cotinine (HY-B1178) . Cotinine N-β-D-Glucuronide is promising for research of tobacco carcinogen metabolism and cognitive function[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Drug Metabolite

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Purity:

  96.64

• Smiles:

  O[C@H]1[C@H]([N+]2=CC=CC([C@H]3N(C(CC3)=O)C)=C2)O[C@@H]([C@H]([C@@H]1O)O)C([O-])=O

• Molecular Formula:

  C16H20N2O7

• Molecular Weight:

  352.34

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Dator R, et al. Metabolomics Profiles of Smokers from Two Ethnic Groups with Differing Lung Cancer Risk. Chem Res Toxicol. 2020 Aug 17;33 (8) :2087-2098.|[2]Huang C, et al. Urinary nicotine metabolites are associated with cognitive impairment among the elderly in southern China. Tob Induc Dis. 2023 Oct 4;21:123.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• CAS Number:

  [139427-57-9]