Dimethomorph-d8
CAT:
804-HY-B0846S
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dimethomorph-d8
- CAS Number: 1346606-71-0
- UNSPSC Description: Dimethomorph-d8 is the deuterium labeled Dimethomorph[1]. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM[2][3][4].
- Target Antigen: Androgen Receptor; Fungal; Parasite
- Type: Isotope-Labeled Compounds
- Related Pathways: Anti-infection;Vitamin D Related/Nuclear Receptor
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Solubility: 10 mM in DMSO
- Smiles: O=C(N1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H])/C=C(C2=CC=C(C=C2)Cl)\C3=CC(OC)=C(C=C3)OC
- Molecular Weight: 395.91
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84(4):454-458.|[3]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun119(6):794-800.|[4]Yigal Cohen,, et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct97(10):1274-83.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported