Dimethomorph

• Description :

  Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Androgen Receptor; Fungal; Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/dimethomorph.html

• Purity :

  99.13

• Solubility :

  DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(N1CCOCC1)/C=C(C2=CC=C(Cl)C=C2)\C3=CC=C(OC)C(OC)=C3

• Molecular Formula :

  C21H22ClNO4

• Molecular Weight :

  387.86

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84 (4) :454-458.|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119 (6) :794-800.|[3]Yigal Cohen, , et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97 (10) :1274-83.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [110488-70-5]