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Dimethomorph

CAT: 0804-HY-B0846-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0846-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].
CAS Number
110488-70-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Androgen Receptor; Fungal; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dimethomorph.html
Purity
99.13
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCOCC1)/C=C(C2=CC=C(Cl)C=C2)\C3=CC=C(OC)C(OC)=C3
Molecular Formula
C21H22ClNO4
Molecular Weight
387.86
Precautions
H302, H315, H319, H335
References & Citations
[1]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84 (4) :454-458.|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119 (6) :794-800.|[3]Yigal Cohen, , et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97 (10) :1274-83.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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