Dimethomorph

• UNSPSC Description:

  Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].

• Target Antigen:

  Androgen Receptor; Fungal; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/dimethomorph.html

• Purity:

  99.13

• Solubility:

  DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(N1CCOCC1)/C=C(C2=CC=C(Cl)C=C2)\C3=CC=C(OC)C(OC)=C3

• Molecular Weight:

  387.86

• References & Citations:

  [1]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84(4):454-458.|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.|[3]Yigal Cohen,, et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97(10):1274-83.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  110488-70-5