Ibudilast-d7-1

CAT: 0804-HY-B0763S2Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0763S2Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ibudilast-d7-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].
CAS Number
[1204192-90-4]
Product Name Alternative
KC-404-d7-1; AV-411-d7-1; MN-166-d7-1
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
CC(C)C(C1=C2N(C=CC=C2)N=C1C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=O
Molecular Formula
C14H11D7N2O
Molecular Weight
237.35
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Mizuno T, et al. Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia. Neuropharmacology. 2004 Mar;46 (3) :404-11.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0763S1Ibudilast-d7
HY-B0763-01Ibudilast
HY-B0763S-01Ibudilast-d3
HY-B0763R-01Ibudilast (Standard)
HY-Y1119S-011-Bromonaphthalene-d7
HY-W016577S31-Bromoheptane-d7
HY-W099504S11-Heptanol-d7
HY-W250096S-011-Iodopropane-d7
HY-Y1309S1-011-Naphthol-d7
HY-B0573S1-01Propranolol-d7 (ring-d7)

Alternative Products

CatalogName
TRC-I125003-1MGIbudilast-d7
C5183-10Ibudilast
RM-I223001-01Ibudilast Impurity 1

Popular Products