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Ceftriaxone-d3 (disodium)

CAT: 0804-HY-B0712SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0712SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceftriaxone-d3 (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics[1][2].
CAS Number
1132650-38-4
Product Name Alternative
Ro 13-9904-d3 (disodium)
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
96.62
Solubility
DMSO : 31.25mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(CSC(N(NC2=O)C)=NC2=O)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC([2H])([2H])[2H])=O)([H])N1C3=O)O[Na].[Na]
Molecular Formula
C18H14D3N8Na2O7S3
Molecular Weight
602.57
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nahata MC, et al. Ceftriaxone: a third-generation cephalosporin. Drug Intell Clin Pharm. 1985;19 (12) :900-906.|[3]Hakimizadeh E, et al. Ceftriaxone improves hepatorenal damages in mice subjected to D-galactose-induced aging. Life Sci. 2020;258:118119.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
β-lactam