Products for Research Use Only
RegisterLogin

Brinzolamide-d5

CAT: 0804-HY-B0588SSize: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0588SSize:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Brinzolamide-d5 is the deuterium labeled Brinzolamide. Brinzolamide (AL 4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.
CAS Number
1217651-02-9
Product Name Alternative
AL-4862-d5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Carbonic Anhydrase; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=S(C(S1)=CC2=C1S(N(CCCOC)C[C@@H]2NC([2H])([2H])C([2H])([2H])[2H])(=O)=O)(N)=O
Molecular Formula
C12H16D5N3O5S3
Molecular Weight
388.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]DeSantis, L., Preclinical overview of brinzolamide. Surv Ophthalmol, 2000. 44 Suppl 2: p. S119-29.|[3]Silver, L.H., Dose-response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt) . Brinzolamide Dose-Response Study Group. Surv Ophthalmol, 2000. 44 Suppl 2: p. S147-53.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
CA II

Related Products

CatalogName
HY-B0588-01Brinzolamide
HY-B0588ABrinzolamide (hydrochloride)
HY-B0588R-01Brinzolamide (Standard)
HY-137966A-01N-Desethyl Brinzolamide (oxalate)
HY-W424792A-01O-Desmethyl Brinzolamide (hydrochloride)
HY-151913S-01Sebuthylazine-d5 (ethyl-d5)
HY-W717221Medetomidine-d5 (d5-Major)
HY-133171AS-01(S) -Norfluoxetine-d5 (phenyl-d5)
HY-151910S1(±) -Fluoxetine-d5 Oxalate (phenyl-d5)
HY-W758414Phoxim-d5 (phenyl-d5) (mixture of isomers)

Alternative Products

CatalogName
004559Brinzolamide-d5
465580-01S-Brinzolamide-d5
CS-O-06447Brinzolamide-d5 Hydrochloride
TRC-B677607-25MG(S)-Brinzolamide (Ethyl-d5)
461248-01O-Desmethyl Brinzolamide-D5
TRC-B677612-5MGO-Desmethyl Brinzolamide-(Ethyl-D5)
263603-01Brinzolamide

Popular Products