Ethambutol-d10

CAT: 0804-HY-B0535S1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0535S1Size:1 mg
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Description
Ethambutol-d10 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
CAS Number
[1129526-24-4]
Product Name Alternative
Emb-d10
UNSPSC
12352211
Target
Antibiotic; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CC[C@](C([2H])([2H])O)([2H])NC([2H])([2H])C([2H])([2H])N[C@@](C([2H])([2H])O)([2H])CC
Molecular Formula
C10H14D10N2O2
Molecular Weight
214.37
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ethambutol. Tuberculosis (Edinb), 2008. 88 (2) : p. 102-5.|[3]Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33 (3) : p. 167-75.|[4]Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17 (1) : p. 51-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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